HFpEF likelihood calculator

Clinical information

Age

years

Sex

Male

Female

BMI

kg/m2

Atrial fibrillation

Yes

From clinical history and EKG

Hypertension

Yes

With ≥ 2 antihypertensive medicines

Echocardiography

Septal e'

cm/s

Lateral e'

cm/s

Septal E/e'

Average E/e'

TR velocity

m/s

Pulmonary artery systolic pressure

mmHg

LAVI

ml/m2

LVMI

g/m2

Relative wall thickness (calculate)

Thickest LV wall

Left ventricular global longitudinal strain

Use only positive values.

Biomarker

Biomarker (choose)

pg/ml

pmol/L

Notification: Missing values are assumed 'zero/normal' for the calculations.

References

ESC HFpEF 2016 score: Ponikowski P, Voors AA, Anker SD, Bueno H, Cleland JG, Coats AJ, Falk V, Gonzalez-Juanatey JR, Harjola VP, Jankowska EA, Jessup M, Linde C, Nihoyannopoulos P, Parissis JT, Pieske B, Riley JP, Rosano GM, Ruilope LM, Ruschitzka F, Rutten FH, van der Meer P; Authors/Task Force Members; Document Reviewers. 2016 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure: The Task Force for the diagnosis and treatment of acute and chronic heart failure of the European Society of Cardiology (ESC). Developed with the special contribution of the Heart Failure Association (HFA) of the ESC. Eur J Heart Fail. 2016 Aug;18(8):891-975. doi: 10.1002/ejhf.592. Epub 2016 May 20. PMID: 27207191.
ESC HFpEF 2021 score: McDonagh, T. A., Metra, M., Adamo, M., Gardner, R. S., Baumbach, A., Bцhm, M., ... & Kathrine Skibelund, A. (2021). 2021 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure: Developed by the Task Force for the diagnosis and treatment of acute and chronic heart failure of the European Society of Cardiology (ESC) With the special contribution of the Heart Failure Association (HFA) of the ESC. European heart journal, 42(36), 3599-3726.
H2FPEF score: Reddy YNV, Carter RE, Obokata M, Redfield MM, Borlaug BA. A Simple, Evidence-Based Approach to Help Guide Diagnosis of Heart Failure With Preserved Ejection Fraction. Circulation. 2018 Aug 28;138(9):861-870. doi: 10.1161/CIRCULATIONAHA.118.034646. PMID: 29792299; PMCID: PMC6202181.
HFA-PEFF score: Pieske B, Tschope C, de Boer RA, Fraser AG, Anker SD, Donal E, Edelmann F, Fu M, Guazzi M, Lam CSP, Lancellotti P, Melenovsky V, Morris DA, Nagel E, Pieske-Kraigher E, Ponikowski P, Solomon SD, Vasan RS, Rutten FH, Voors AA, Ruschitzka F, Paulus WJ, Seferovic P, Filippatos G. How to diagnose heart failure with preserved ejection fraction: the HFA-PEFF diagnostic algorithm: a consensus recommendation from the Heart Failure Association (HFA) of the European Society of Cardiology (ESC). Eur Heart J. 2019 Oct 21;40(40):3297-3317. doi: 10.1093/eurheartj/ehz641. PMID: 31504452.

Version 2.2. 23-12-2022. Error fixed: H2FPEF score now uses septal instead of lateral E/e'. Changelog available on request.

Disclaimer: This calculator is developed to reproduce diagnostic scores solely based on published algorithms (see References). The calculator itself does not diagnose patients or suggest treatments, and is not responsible nor substitute any medical decisions or clinical judgement made. Calculations must be re-assessed for patient care.